I'm re-installing SOA suite 18.104.22.168.
The OSB I have is 22.214.171.124. (ofm_osb_generic_126.96.36.199.0_disk1_1of1.zip)
While installing OSB I encountered this "specified oepe location is not a valid location". However, the location I point to is the matching version 188.8.131.52 OEPE (oepe-galileo-all-in-one-184.108.40.206.0.201001281326-win32).
After struggling for a long time, I downloaded oepe-helios-all-in-one-220.127.116.11.1.201010012100-win32.zip, that did the trick.
I am not sure you see the irony, the matching verion OEPE doesn't work with OSB. I had to use a higher version OEPE 18.104.22.168. oh, well :-(